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Table of contents

Crackles, Instabilities and Recruitment in the Lung
Crackle Sound During Lung Inflation
Introduction: Lung Crackles
PowerPoint Presentation
Airway Closure
Experimental Setup
Example of crackle time series
Crackle Features
Inter-crackle Intervals
Model
Avalanches & the Active Surface
Distribution of the Inter-Crackle intervals
In Vivo Human Crackles
Conclusions (1/3)
Instabilities
Lung Instabilities and Recruitment
Basic Concept
Slide 18
Example of the Pressure-Volume Curve in One Lung: slow inflation
Negative Elastance
Slide 21
Avalanche
The Algorithm of Volume Controlled Inflation
Pressure-Volume Curve of the Model
Distribution of Negative Elastances: Experiment and Model
Conclusions (2/3)
Recruitment
Slide 28
Acute Respiratory Distress Syndrome (ARDS)
Current Ventilation Strategies
“Biologic Variability” in Mechanical Ventilation
Noisy Ventilation
Slide 33
Ventilation Methods
Slide 35
Stochastic Resonance in Blood Oxygenation
Slide 37
Experimental Methods II
Lung Physiology Results
Slide 40
Slide 41
Conclusions (3/3)

Author: Adriano M. Alencar